154: A survey assessment of patients’ knowledge of trisomy 21 at first trimester screen ultrasound

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Two-stage first-trimester screening for trisomy 21 by ultrasound assessment and biochemical testing.

OBJECTIVES This study was carried out to examine the performance of a contingent policy in first-trimester screening for trisomy 21, in which the estimated risk was first derived by a combination of maternal age, fetal nuchal translucency (NT) thickness, presence/absence of the nasal bone, blood flow in the ductus venosus or flow across the tricuspid valve, and biochemical testing was carried o...

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Variation of Ultrasound Findings in the First Trimester Examination of Recurrent Cases With Trisomy 21

Increased nuchal translucency (NT) is present in about 50% of cases with trisomy 21. Very often the nuchal edema evolves in hydrops fetalis until the second trimester. Furthermore, a small amount of cases with a normal NT and trisomy 21 exhibit anatomical anomalies. We present a case of a 21-year-old woman, nulliparous, with a history of one termination of pregnancy and a smoking quitter. The p...

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First Trimester Diagnosis of Trisomy-21 Using Artificial Neural Networks

A chromosomal disorder caused by the presence of all or part of an extra 21st chromosome is known as the Down syndrome, or trisomy 21, or trisomy G. In the last fifteen years it has become possible to observe these features by ultrasound examination in the third month of intrauterine life. About 75% of trisomy 21 fetuses have absent nasal bone. In the present work, neural network schemes that h...

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Prospective first-trimester screening for trisomy 21 in 30,564 pregnancies.

OBJECTIVE This study was undertaken to evaluate the performance of a 1-stop clinic for first-trimester assessment of risk (OSCAR) for trisomy 21 by a combination of maternal age, fetal nuchal translucency (NT) thickness, and maternal serum-free ss- human chorionic gonadotrophin (hCG) and pregnancy-associated plasma protein-A (PAPP-A). STUDY DESIGN OSCAR was carried out in 30,564 pregnancies a...

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ژورنال

عنوان ژورنال: American Journal of Obstetrics and Gynecology

سال: 2020

ISSN: 0002-9378

DOI: 10.1016/j.ajog.2019.11.170